刘 青 业

刘青业

理学博士，校特聘副教授，硕士生导师

研究方向：多糖基药物、基因载体；水凝胶功能材料

联系电话：86-15834123748

Email:qingyeliu@126.com

教育与研究经历

2003.9-2007.6，理学学士，西南大学化学化工学院

2007.8-2009.6 化学教师，酒都高级中学

2009.9-2014.6，理学博士，武汉大学化学与分子科学学院

2014.6 -至今，讲师、校特聘副教授，硕导，中北大学化工与环境学院

2016.10-2019.4，博士后研究助理，Texas Tech University Department of Chemical Engineering

研究领域与兴趣

1、多糖基药物、基因载体

2、多糖/纳米粒子复合物抗癌机理

3、高强度水凝胶植入材料的构建

承担项目

1、 国家自然科学青年基金（51603195），基于酵母β-葡聚糖与蛋白质间的相互作用构建口服蛋白类药物载体及其功能研究，2017.1-2019.12。（主持）

2、 国家自然科学基金（21274114），Beta-葡聚糖的链结构、抗炎症活性及其与靶标受体分子的相互作用研究，2013.1-2016.12。（参与）

代表性论文

1. Qingye Liu, Xing Zheng, Xiaojuan Xu* Recent Progress in Polysaccharide-Nanocomposites with Therapeutic Function. J Mater. Chem. B, 2017, invited review.

2. Qingye Liu, Xiaojuan Xu*. Recent progress in chain conformation and function of the triple helical glucans.Journal of Functional Polymers, 2016,29, 134-152.

3. Xing Zheng, Siwei Zou, Hui Xu, Qingye Liu, Jianhui Song, Min Xu, Xiaojuan Xu*, Lina Zhang. The linear structure of β-glucan from baker’s yeast and its activation of macrophage-like RAW264. 7 cells. Carbohydr. Polym.,2016, 148, 61-68.

4. Qingye Liu, Hui Xu, Yan Cao,Mengxia Li, Xiaojuan Xu*, Lina Zhang.Transfection efficiency and internalization of the gene carrier prepared from a triple helical b-glucan and polydeoxyadenylic acid in macrophage RAW264.7 cells. J Mater. Chem. B2015,3, 3789-3798.

5. Qingye Liu, Chaoqun Wang, Yan Cao, Xiaojuan Xu*, Lina Zhang. A novel gene carrier prepared from triple helical b-glucan and polydeoxyadenylic acid. J Mater. Chem. B 2014, 2, 933-944. (cover paper)

6. Qingye Liu, Xiaojuan Xu*, Lina Zhang, Xudong Luo, Yi Liang. Assembly of single-stranded polydeoxyadenylic acid and β-glucan probed by the sensing platform of graphene oxide based on the fluorescence resonance energy transfer and fluorescence anisotropy. Analyst, 2013, 138, 2661-2668.

7. Qingye Liu, Meng He, Xiaojuan Xu* , Lina Zhang , Junping Yu Self-assembly of graphene oxide on the surface of aluminum foil. New J. Chem., 2013, 37, 181-187.

8. Qingye Liu, Xiaojuan Xu*, Lina Zhang. Variable chain conformations of renatured b-glucan in dimethylsulfoxide/water mixture.Biopolymers2012, 97, 988-997.

9. Qingye Liu, Xiaojuan Xu*, Lina Zhang, Junping Yu. Interaction between polydeoxyadenylic acid and b-glucan from Lentinusedodes.Eur.Polym. J.2012, 48, 1329-1338.

10. XueweiJia, Qingye Liu, Siwei Zou, Xiaojuan Xu*, Lina Zhang, Construction of selenium nanoparticles/b-glucan composites for enhancement of the antitumor activity, Carbohydr. Polym., 2015, 117, 434-442.

11. Di Wu, Xiang Deng, Xiaomei Huang, Kun Wang, Qingye Liu. Low-Cost Preparation of Photoluminescent Carbon Nanodots and Application as Peroxidase Mimetics in Colorimetric Detection of H2O2 and Glucose. J. Nanosci. Nanotechnol. 2013, 13, 6611-6616.

12. Di Wu, Xiaomei Huang,Xiang Deng,Kun Wang, Qingye Liu. Preparation of photoluminescent carbon nanodots by traditional Chinese medicine and application as a probe for Hg2+. Anal. Methods, 2013, 5, 3023-3027.

13. Longqiang Xiao, ShaojunCai, Qingye Liu, Liqiong Liao, Xin Guo, Yan Li, XiangxiangJia, Feifei Li, Lijian Liu.One-step synthesis of polypyrazole and self-assembled polypyrazole-copper catalyst for click chemistry. Polym. Chem., 2014, 5, 607-613.