荀苗苗

1、个人简介

荀苗苗，女，1986年生，山西霍州人，博士，讲师，2016年毕业于四川大学。现就职于中北大学化学工程与技术学院，药物绿色合成工艺创新团队的成员，山西省抗癌协会肿瘤纳米学专业委员会委员。主要研究方向为具有“门禁”和磁靶向的多功能介孔SiO₂载体构建及其基因/药物共传递研究。目前主持山西省高等学校科技创新项目1项，参与国家自然科学基金青年基金项目1项，参与山西省自然科学基金面上青年基金项目2项，截止目前以第一作者或通讯作者的身份发表SCI论文6篇。

2、教育经历

2011.09-2016.06 四川大学有机化学专业 博士学位（硕博连读）

2007.09-2011.07 安阳师范学院材料化学专业 学士学位

3、工作经历

2016.06至今 中北大学化学工程与技术学院 讲师

4、代表性科研成果

（1）Miao-Miao Xun, Yunli Bai, Yanhong Wang, Zhiyong Hu, Kai Fu, Wenbing Ma, and Changchun Yuan^*.Synthesis of Four Illudalane Sesquiterpenes Utilizing a One-Pot Diels−Alder/Oxidative Aromatization Sequence.Org. Lett.2019,21, 6879−6883.

（2）Miao-Miao Xun^*, Zheng Huang, Ya-Ping Xiao, Yan-Hong Liu, Ji Zhang^*, Ju-Hui Zhang, Xiao-Qi Yu^*. Synthesis and properties of low molecular weight PEI-based-lipopolymers for delivery of DNA.Polymers,2018, 10,1060.

（3）Miao-Miao Xun, Ju-Hui Zhang, Yan-Hong Liu, Ji Zhang^*, Ya-Ping Xiao, Qian Guo, Shuo Li, Xiao-Qi Yu^*. Polyethylenimine analogs for improved gene delivery: Effect of the type of amino groups.RSC Adv.,2016,6, 5391-5400.

（4）Miao-Miao Xun, Ya-Ping Xiao, Ji Zhang^*, Yan-Hong Liu, Qi Peng, Qian Guo, Wan-Xia Wu, Yong Xu, Xiao-Qi Yu^*. Low molecular weight PEI-based polycationic gene vectors via Michael addition polymerization with improved serum-tolerance.Polymer,2015,65, 45-54.

（5）Miao-Miao Xun, Yan-Hong Liu, Qian Guo, Ji Zhang^*, Qin-Fang Zhang, Wan-Xia Wu, Xiao-Qi Yu^*. Low molecular weight PEI-appended polyesters as non-viral gene delivery vectors.European Journal of Medicinal Chemistry,2014,78, 118-125.

（6）Miao-Miao Xun, Xue-Chao Zhang, Ji Zhang^*, Qian-Qian Jiang, Wen-jing Yi, Wen Zhu^*, Xiao-Qi Yu^*.Low molecular weight PEI-based biodegradable lipopolymers as gene delivery vectors.Org. Biomol. Chem.2013,11, 1242-1250.

（7）袁长春,钟上勇,王艳红,荀苗苗*.基于生育酚修饰的的低分子量聚乙烯亚胺基因载体,科学技术与工程，2018,18(29), 1671-1815.

（8）Changchun Yuan*, Shangyong Zhong, Xingying Li, Yanhong Wang,Miao-Miao Xun, Yunli Bai, Kongkai Zhu, Total synthesis, structural revision and biological evaluation of gamma-elemene-type sesquiterpenes,Org. Biomol. Chem.,2018,16(42), 7843-7850.

（9）Changchun Yuan, Biao Du,Miao-Miao Xun, Bo Liu*, Oxidative cleavage of hydroxamic acid promoted by sodium periodate,Tetrahedron,2017,73(26), 3622-3628.

（10）Yunli Bai, Yanhong Wang, Xingyi Li,Miao-Miao Xun, Changchun Yuan*, Crystal structure ofrac-3,6-dimethyl-5-(prop-1-en-2-yl)-6-vinyl-1,4,5,6- tetrahydro-2H-indol-2-one, C₁₅H₁₉NO,Z. Kristallogr. NCS,2019,234(3), 419-420.

（11）Qian Guo, Yan-Hong Liu,Miao-Miao Xun, Ji Zhang, Zheng Huang, Xue-Dong Zhou, Xiao-Qi Yu. Diol glycidyl ether-bridged low molecular weight PEI as potential gene delivery vehicles.J. Mater. Chem. B,2015,3, 2660-2670.

（12）Bing Wang, Wen-Jing Yi, Ji Zhang, Qin-Fang Zhang,Miao-Miao Xun, Xiao-Qi Yu. TACN-based cationic lipids with amino acid backbone and double tails: Materials for non-viral gene delivery.Bioorg. Med. Chem. Lett.2014,24, 1771-1775.

（13）Wan-Xia Wu, Xian-Ling Yang, Bei-Yu Liu, Qing-Feng Deng,Miao-Miao Xun, Na Wang, Xiao-Qi Yu. Lipase-catalyzed synthesis of oxidation-responsive poly(ethylene glycol)-b-poly(b-thioether ester) amphiphilic block copolymers.RSC Adv.,2016,6, 11870-11879.

5、联系方式

邮箱：xunmiaomiao@163.com